KLK6 Polyclonal Antibody

CAT: 0866-RD80772A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD80772A-01Size:60 μL
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Background
This gene encodes a member of the kallikrein subfamily of the peptidase S1 family of serine proteases. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The encoded preproprotein is proteolytically processed to generate the mature protease. Expression of this protease is regulated by steroid hormones and may be elevated in multiple human cancers and in serum from psoriasis patients. The encoded protease may participate in the cleavage of amyloid precursor protein and alpha-synuclein, thus implicating this protease in Alzheimer's and Parkinson's disease, respectively. This gene is located in a gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Description
This is a KLK6 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
KLK6, Bssp, Klk7, PRSS18, PRSS9, SP59, hK6
Gene ID
5653
Swiss Prot
Q92876
Reactivity
Human
Immunogen
A synthetic peptide of human KLK6 (NP_002765.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
4 kDa/15 kDa/26 kDa
Observed Molecular Weight
27 kDa
Host or Source
Rabbit
Isotype
IgG

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