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ASC / TMS1 Polyclonal Antibody

CAT: 0866-RD80686A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD80686A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD) . The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene.
Description
This is a ASC / TMS1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
PYCARD, ASC, CARD5, TMS, TMS-1, TMS1, PYD and CARD domain containing, ASC / TMS1
Gene ID
29108
Swiss Prot
Q9ULZ3
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human ASC / TMS1 (NP_037390.2) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000 IF 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
15 kDa/19 kDa/21 kDa
Observed Molecular Weight
22 kDa
Host or Source
Rabbit
Isotype
IgG

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