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TNFR2 Polyclonal Antibody

CAT: 0866-RD80497A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD80497A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.
Description
This is a TNFR2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
CD120b, TBPII, TNF-R-II, TNF-R75, TNFBR, TNFR1B, TNFR2, TNFR80, p75, p75TNFR, TNF Receptor II, TNFRSF1B
Gene ID
7133
Swiss Prot
P20333
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human TNFRSF1B
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
28 kDa/48 kDa
Observed Molecular Weight
64 kDa
Host or Source
Rabbit
Isotype
IgG

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