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PTCH1 Polyclonal Antibody

CAT: 0866-RD80143A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD80143A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. This gene functions as a tumor suppressor. Mutations of this gene have been associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences and biological validity cannot be determined currently.
Description
This is a PTCH1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
PTCH1, BCNS, HPE7, NBCCS, PTC, PTC1, PTCH, PTCH11, patched 1
Gene ID
5727
Swiss Prot
Q13635
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human PTCH1 (NP_000255.2) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
IHC 1:50-1:100 IF 1:50-1:100
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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