RAD50 Polyclonal Antibody

CAT: 0866-RD79963A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD79963A-01Size:60 μL
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder.
Description
This is a RAD50 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
RAD50, NBSLD, RAD502, hRad50
Gene ID
10111
Swiss Prot
Q92878
Reactivity
Human, Mouse
Immunogen
A synthetic peptide of human RAD50
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000 IHC 1:50-1:100
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
138 kDa/153 kDa/154 kDa
Observed Molecular Weight
180 kDa
Host or Source
Rabbit
Isotype
IgG

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