HDAC4 Polyclonal Antibody

• Background :

  Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.

• Description :

  This is a HDAC4 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  HDAC4, AHO3, BDMR, HA6116, HD4, HDAC-4, HDAC-A, HDACA

• Gene ID :

  9759

• Swiss Prot :

  P56524

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein of human HDAC4 (NP_006028.2) .

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  IHC

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  1 mg/mL

• Dilution :

  IHC 1:50-1:100

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source :

  Rabbit

• Isotype :

  IgG