HDAC4 Polyclonal Antibody

• Background:

  Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.

• Description:

  This is a HDAC4 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  HDAC4, AHO3, BDMR, HA6116, HD4, HDAC-4, HDAC-A, HDACA

• Gene ID:

  9759

• Swiss Prot:

  P56524

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human HDAC4 (NP_006028.2) .

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  IHC

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  IHC 1:50-1:100

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source:

  Rabbit

• Isotype:

  IgG