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JNK2 Polyclonal Antibody

CAT: 0866-RD79933A-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0866-RD79933A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells.JNK2 isoforms display different binding patterns: alpha-1 and alpha-2 preferentially bind to c-Jun, whereas beta-1 and beta-2 bind to ATF2. However, there is no correlation between binding and phosphorylation, which is achieved at about the same efficiency by all isoforms. JUNB is not a substrate for JNK2 alpha-2, and JUND binds only weakly to it.
Description
This is a JNK2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
C Jun kinase 2, C Jun N terminal kinase 2, c-Jun N-terminal kinase 2, JNK 55, JNK-55, JNK2 alpha, JNK2, JNK2 beta, JNK2A, JNK2alpha, JNK2B, JNK2BETA, Jun kinase, MAP kinase 9, MAPK 9, Mapk9, Mitogen activated protein kinase 9, Mitogen-activated protein kinase 9, MK09, P54a
Swiss Prot
P45984
Accession Number
NP_620707
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide of human MAPK9
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.4 mg/mL
Dilution
WB 1:500-1:2000, IHC 1:25-1:100
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
48 kDa
Observed Molecular Weight
Refer to figures
Host or Source
Rabbit
Isotype
IgG

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