TTI1 Polyclonal Antibody

• Background:

  Regulator of the DNA damage response (DDR) . Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC) . Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals.

• Description:

  This is a TTI1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  Smg-10, KIAA0406

• Swiss Prot:

  O43156

• Accession Number:

  NP_055472

• Reactivity:

  Human, Mouse

• Immunogen:

  Synthetic peptide of human TTI1

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  IHC, ELISA

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1.2 mg/mL

• Dilution:

  IHC 1:30-150, ELISA 1:2000-10000

• Buffer:

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source:

  Rabbit

• Isotype:

  IgG