TTI1 Polyclonal Antibody

CAT: 0866-RD79748A-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:0866-RD79748A-01Size:20 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Regulator of the DNA damage response (DDR) . Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC) . Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals.
Description
This is a TTI1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
Smg-10, KIAA0406
Swiss Prot
O43156
Accession Number
NP_055472
Reactivity
Human, Mouse
Immunogen
Synthetic peptide of human TTI1
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1.2 mg/mL
Dilution
IHC 1:30-150, ELISA 1:2000-10000
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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