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LRP6 Polyclonal Antibody

CAT: 0866-RD79663A-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0866-RD79663A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.
Description
This is a LRP6 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
ADCAD2, C030016K15Rik, Cd, FLJ90062, FLJ90421, LDL receptor related protein 6, Low density lipoprotein receptor related protein 6, Low-density lipoprotein receptor-related protein 6, LRP-6, LRP6, LRP6, OTTHUMP00000238979, OTTHUMP00000238980, OTTHUMP00000238982, STHAG7
Swiss Prot
O75581
Accession Number
BC143725
Reactivity
Human, Mouse
Immunogen
Synthetic peptide of human LRP6
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1.4 mg/mL
Dilution
IHC 1:40-200, ELISA 1:2000-10000
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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