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TIRAP Polyclonal Antibody

CAT: 0866-RD79496A-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0866-RD79496A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described.
Description
This is a TIRAP Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
Adapter protein wyatt, FLJ42305, MAL, MyD88 adapter like protein, TIR domain containing adapter protein, Toll interleukin 1 receptor (TIR) domain containing adaptor protein, Toll interleukin 1 receptor domain containing adapter protein, Toll like receptor adapto
Swiss Prot
P58753
Accession Number
BC032474
Reactivity
Human
Immunogen
Full length fusion protein
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.5 mg/mL
Dilution
IHC 1:25-100, ELISA 1:2000-5000
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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