PPOX Polyclonal Antibody

• Background:

  This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified.

• Description:

  This is a PPOX Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  MGC8485, PPO, PPOX, PPOX, Protoporphyrinogen oxidase, V290M, Variegate porphyria, VP

• Swiss Prot:

  P50336

• Accession Number:

  NP_000300

• Reactivity:

  Human, Mouse

• Immunogen:

  Synthetic peptide of human PPOX

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IHC, ELISA

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  0.5 mg/mL

• Dilution:

  WB 1:1000-1:5000, IHC 1:50-1:200

• Buffer:

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  51 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG