CD2AP Polyclonal Antibody

• Background:

  This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease.

• Description:

  This is a CD2AP Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  Adapter protein CMS, AL024079, C78928, Cas ligand with multiple SH3 domains, CD2 associated protein, CD2-associated protein, CD2AP, CD2AP, CMS, Mesenchyme to epithelium transition protein with SH3 domains 1, METS 1, Mets1

• Swiss Prot:

  Q9Y5K6

• Accession Number:

  NP_036252

• Reactivity:

  Human

• Immunogen:

  Synthetic peptide of human CD2AP

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IHC, ELISA

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  0.2 mg/mL

• Dilution:

  WB 1:1000-1:5000, IHC 1:100-1:300

• Buffer:

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  71 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG