Products for Research Use Only

DCC Polyclonal Antibody

CAT: 0866-RD78669A-01Size: 20 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0866-RD78669A-01Size:20 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
This gene encodes a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules, and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand. The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK, also known as PTK2) to mediate axon attraction. The protein partially localizes to lipid rafts, and induces apoptosis in the absence of ligand. The protein functions as a tumor suppressor, and is frequently mutated or downregulated in colorectal cancer and esophageal carcinoma.
Description
This is a DCC Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
Colorectal cancer related chromosome sequence 18, Colorectal cancer suppressor, CRC 18, CRC18, CRCR 1, CRCR1, DCC, DCC, Deleted in colorectal cancer protein, Deleted in colorectal carcinoma, Immunoglobulin superfamily DCC subclass member 1, Netrin receptor DCC, Tumor
Swiss Prot
P43146
Accession Number
NP_005206
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide of human DCC
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.7 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

Popular Products