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SOCS1 Polyclonal Antibody

CAT: 0866-RD78638A-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0866-RD78638A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN) -gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival.
Description
This is a SOCS1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
CISH 1, CISH1, Cytokine inducible SH2 protein 1, JAB, JAK binding protein, JAK-binding protein, Janus kinase binding protein, SOCS 1, SOCS-1, Socs1, SOCS1, SSI 1, SSI-1, SSI1, STAT induced STAT inhibitor 1, STAT-induced STAT inhibitor 1, Suppressor of cytokine signaling
Swiss Prot
O15524
Accession Number
NP_003736
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide of human SOCS1
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.6 mg/mL
Dilution
WB 1:500-1:2000, IHC 1:100-1:300
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
24 kDa
Host or Source
Rabbit
Isotype
IgG

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