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SMAD7 Polyclonal Antibody

CAT: 0866-RD78637A-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0866-RD78637A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3) . Several transcript variants encoding different isoforms have been found for this gene.
Description
This is a SMAD7 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
CRCS3, FLJ16482, hSMAD 7, hSMAD7, MAD (mothers against decapentaplegic Drosophila) homolog 7, MAD, Mad homolog 7, MAD homolog 8, MAD mothers against decapentaplegic homolog 7, MADH 7, MADH 8, MADH6, MADH8, Mothers Against Decapentaplegic Drosophila Homolog of 6, Mother
Swiss Prot
O15105
Accession Number
NP_005895
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide of human SMAD7
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.4 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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