C-Fms Polyclonal Antibody

• Background:

  The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction.

• Description:

  This is a c-Fms Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  C FMS, CD 115, CD115, CD115 antigen, CFMS, Colony stimulating factor 1 receptor, Colony stimulating factor I receptor, CSF 1 R, CSF 1R, CSF-1 receptor, CSF-1-R, CSF1 R, CSF1R, CSF1R, CSFR, EC 2.7.10.1, FIM 2, FIM2, FMS, FMS proto oncogene, FMS protooncogene, HDLS, M-CSF Recept

• Swiss Prot:

  P07333

• Accession Number:

  NP_005202

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Synthetic peptide of human CSF1R

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, ELISA

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  0.5 mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  108 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG