PPP1R13L Polyclonal Antibody

• Background:

  RelA-associated inhibitor is a protein that in humans is encoded by the PPP1R13L gene. Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis. Interacts with RELA NF-kappa-B subunit and with SP1 via its C-terminus part. Interacts with p53/TP53, TP63 and TP73.

• Description:

  This is a PPP1R13L Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  IASPP, inhibitor of apoptosis stimulating protein of p53, Inhibitor of ASPP protein, NFkB interacting protein 1, NKIP1, PPP1R13B-like protein, PPP1R13L, Protein iASPP, protein phosphatase 1 regulatory (inhibitor) subunit 13 like, RAI, RelA-associated inhibitor

• Swiss Prot:

  Q8WUF5

• Accession Number:

  NP_006654

• Reactivity:

  Human, Mouse

• Immunogen:

  Synthetic peptide of human PPP1R13L

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IHC, ELISA

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  0.6 mg/mL

• Dilution:

  WB 1:500-1:2000, IHC 1:50-1:200

• Buffer:

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  89 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG