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GNRHR Polyclonal Antibody

CAT: 0866-RD78531A-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0866-RD78531A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH) . Defects in this gene are a cause of hypogonadotropic hypogonadism (HH) . Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene.
Description
This is a GNRHR Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
GnRH receptor, GnRH-R, GNRHR, GNRHR, GNRHR1, Gonadotropin releasing hormone receptor, gonadotropin-releasing hormone (type 1) receptor 1, Gonadotropin-releasing hormone receptor, GRHR, HH7, leutinizing-releasing hormone receptor, lh-rh, LHRHR, LRHR, luliberin receptor
Swiss Prot
P30968
Accession Number
NP_000397
Reactivity
Human, Mouse
Immunogen
Synthetic peptide of human GNRHR
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.9 mg/mL
Dilution
WB 1:2000-1:5000, IHC 1:150-1:500
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
28 kDa
Host or Source
Rabbit
Isotype
IgG

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