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GAD2 Polyclonal Antibody

CAT: 0866-RD78507A-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0866-RD78507A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.
Description
This is a GAD2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
65 kDa glutamic acid decarboxylase, DCE 2, DCE2, DCE2, GAD 2, GAD 65, GAD-2, GAD-65, Gad2, Glutamate decarboxylase 2 (pancreas), Glutamate Decarboxylase 2 (pancreatic islets and brain 65kDa), Glutamate decarboxylase 2, Glutamate Decarboxylase 65, Glutamate decarboxyla
Swiss Prot
Q05329
Accession Number
NP_000809
Reactivity
Human
Immunogen
Synthetic peptide of human GAD2
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.3 mg/mL
Dilution
IHC 1:25-1:100
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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