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NPR1 Polyclonal Antibody

CAT: 0866-RD78422A-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0866-RD78422A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Guanylyl cyclases, catalyzing the production of cGMP from GTP, are classified as soluble and membrane forms . The membrane guanylyl cyclases, often termed guanylyl cyclases A through F, form a family of cell-surface receptors with a similar topographic structure: an extracellular ligand-binding domain, a single membrane-spanning domain, and an intracellular region that contains a protein kinase-like domain and a cyclase catalytic domain. GC-A and GC-B function as receptors for natriuretic peptides; they are also referred to as atrial natriuretic peptide receptor A (NPR1) and type B (NPR2; MIM 108961) . Also see NPR3 (MIM 108962), which encodes a protein with only the ligand-binding transmembrane and 37-amino acid cytoplasmic domains. NPR1 is a membrane-bound guanylate cyclase that serves as the receptor for both atrial and brain natriuretic peptides (ANP (MIM 108780) and BNP (MIM 600295), respectively) .
Description
This is a NPR1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
ANP-A, ANPa, ANPR-A, ANPRA, ANPRA, Atrial natriuretic peptide A type receptor, Atrial natriuretic peptide receptor 1, Atrial natriuretic peptide receptor A, Atrial natriuretic peptide receptor type A, Atrionatriuretic peptide receptor A, GC A, GC-A, Guanylate cyclase
Swiss Prot
P16066
Accession Number
NP_000897
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide of human NPR1
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.4 mg/mL
Dilution
IHC 1:25-1:100
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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