DNAJC15 Polyclonal Antibody

CAT: 0866-RD78126A-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:0866-RD78126A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The DnaJ family is one of the largest of all the chaperone families and has evolved with diverse cellular localization and functions. The presence of a J domain defines a protein as a member of the DnaJ family. DnaJ heat shock induced proteins are from the bacterium Escherichia coli and are under the control of the htpR regulatory protein. The DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP hydrolysis. DnaJ proteins are important mediators of proteolysis and are involved in the regulation of protein degradation, exocytosis and endocytosis. MCJ (methylation-controlled J protein), also known as HSD18, DNAJD1 or DNAJC15, is a 150 amino acid ubiquitously expressed single-pass membrane protein containing one J domain. Localizing to the golgi apparatus and only present in vertebrates, MCJ may be associated with increased chemotherapeutic resistance in ovarian cancer by inducing expression of the Mdr drug transporter and preventing intracellular drug accumulation.
Description
This is a DNAJC15 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
Cell growth inhibiting gene 22 protein, Cell growth-inhibiting gene 22 protein, DJC15, DnaJ (Hsp40) homolog subfamily C member 15, DNAJ domain containing, DnaJ homolog subfamily C member 15, DNAJC15, DNAJD1, GIG22, HSD18, MCJ, Methylation controlled J protein, Methyl
Swiss Prot
Q9Y5T4
Accession Number
BC010910
Reactivity
Human, Mouse
Immunogen
Recombinant protein of human DNAJC15
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.3 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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