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GCK Polyclonal Antibody

CAT: 0866-RD78120A-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0866-RD78120A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), maturity onset diabetes of the young, type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI) .
Description
This is a GCK Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
ATP:D-hexose 6-phosphotransferase, FGQTL3, GCK, GK, GLK, Glucokinase, Hexokinase D pancreatic isozyme, Hexokinase type IV, Hexokinase-4, Hexokinase-D, HHF3, HK IV, HK4, HKIV, HXK4, HXKP, LGLK, MODY2
Swiss Prot
P35557
Accession Number
BC001890
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of human GCK
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.4 mg/mL
Dilution
IHC 1:100-1:300
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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