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EID1 Polyclonal Antibody

CAT: 0866-RD78043A-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0866-RD78043A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
E1A-like inhibitor of differentiation-1 (EID-1), an acetyltransferase enzyme, binds both the retinoblastoma protein (Rb), a regulator of cell cycle and tissue specific transcription, and the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. EID-1 inhibits cellular differentiation by blocking the histone acetyltransferase activity of p300. EID-1 also acetylates both histones and non-histone proteins such as NCOA3 co-activator. By acetylating histones, EID-1 gives a specific tag for transcriptional activation. In addition to binding Rb and p300, EID-1 also binds to phosphorylated CREB protein, mediating cAMP gene regulation. EID-1 augments the activity of phosphorylated CREB and activates transcription of cAMP responsive genes as a co-activator.
Description
This is a EID1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
21 kDa pRb associated protein,21 kDa pRb-associated protein, C15orf3, CBP, Chromosome 15 open reading frame 3, CREBBP/EP300 inhibitor 1, CREBBP/EP300 inhibitory protein 1, CRI 1, CRI1, E1A like inhibitor of differentiation, E1A-like inhibitor of differentiation 1
Swiss Prot
Q9Y6B2
Accession Number
NP_055150
Reactivity
Human
Immunogen
Recombinant protein of human EID1
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.6 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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