EID1 Polyclonal Antibody

• Background:

  E1A-like inhibitor of differentiation-1 (EID-1), an acetyltransferase enzyme, binds both the retinoblastoma protein (Rb), a regulator of cell cycle and tissue specific transcription, and the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. EID-1 inhibits cellular differentiation by blocking the histone acetyltransferase activity of p300. EID-1 also acetylates both histones and non-histone proteins such as NCOA3 co-activator. By acetylating histones, EID-1 gives a specific tag for transcriptional activation. In addition to binding Rb and p300, EID-1 also binds to phosphorylated CREB protein, mediating cAMP gene regulation. EID-1 augments the activity of phosphorylated CREB and activates transcription of cAMP responsive genes as a co-activator.

• Description:

  This is a EID1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  21 kDa pRb associated protein,21 kDa pRb-associated protein, C15orf3, CBP, Chromosome 15 open reading frame 3, CREBBP/EP300 inhibitor 1, CREBBP/EP300 inhibitory protein 1, CRI 1, CRI1, E1A like inhibitor of differentiation, E1A-like inhibitor of differentiation 1

• Swiss Prot:

  Q9Y6B2

• Accession Number:

  NP_055150

• Reactivity:

  Human

• Immunogen:

  Recombinant protein of human EID1

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  IHC, ELISA

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  0.6 mg/mL

• Dilution:

  IHC 1:50-1:200

• Buffer:

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source:

  Rabbit

• Isotype:

  IgG