Products for Research Use Only
RegisterLogin

CPSF4 Polyclonal Antibody

CAT: 0866-RD77978A-01Size: 20 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0866-RD77978A-01Size:20 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Inhibition of the nuclear export of poly (A) -containing mRNAs caused by the influenza A virus NS1 protein requires its effector domain. The NS1 effector domain functionally interacts with the cellular 30 kDa subunit of cleavage and polyadenylation specific factor 4, an essential component of the 3' end processing machinery of cellular pre-mRNAs. In influenza virus-infected cells, the NS1 protein is physically associated with cleavage and polyadenylation specific factor 4, 30kD subunit. Binding of the NS1 protein to the 30 kDa protein in vitro prevents CPSF binding to the RNA substrate and inhibits 3' end cleavage and polyadenylation of host pre-mRNAs. Thus the NS1 protein selectively inhibits the nuclear export of cellular, and not viral, mRNAs. Multiple alternatively spliced transcript variants that encode different isoforms have been described for this gene.
Description
This is a CPSF4 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
Cleavage and polyadenylation specific factor 4,30kDa, Cleavage and polyadenylation specificity factor 30 kDa subunit, Cleavage and polyadenylation specificity factor subunit 4, cleavage polyadenylation specificity factor,30kD, CPSF 30 kDa subunit, CPSF30, Cpsf4
Swiss Prot
O95639
Accession Number
BC003101
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of human CPSF4
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.4 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
30 kDa
Host or Source
Rabbit
Isotype
IgG

Related Products

CatalogName
RD87459A-01CPSF3 Polyclonal Antibody
RD266878A-01Cpsf4l Polyclonal Antibody
RD83597A-01CPSF6 Polyclonal Antibody
RD81942A-01Polyclonal AntibodyPC1 Polyclonal Antibody
RD83593A-01Polyclonal AntibodyPC4 Polyclonal Antibody
RD77496A-01MAG Polyclonal Antibody
RD77501A-01MCM6 Polyclonal Antibody
RD219935A-01ATP5I Polyclonal Antibody
RD75037A-01TONSL Polyclonal Antibody
RD218583A-01CALHM1 Polyclonal Antibody

Alternative Products

CatalogName
MBS8566396-01CPSF4 Polyclonal Antibody
NBP2-57038Rabbit Polyclonal CPSF4 Antibody
GTR17868636CPSF4 Rabbit Polyclonal Antibody
TMAB-04620-01Anti-CPSF4 Polyclonal Antibody

Popular Products