Products for Research Use Only

SYT4 Polyclonal Antibody

CAT: 0866-RD77600A-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0866-RD77600A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Synaptotagmins are a large gene family of synaptic vesicle type III integral membrane proteins that function as regulators of both exocytosis and endocytosis and are involved in neurotransmitter secretion from small secretory vesicles. Calcium binds to Synaptotagmin I which triggers neurotransmitter release at the synapse. Synaptotagmin II is phosphorylated by WNK1 in a process that regulates calcium-dependent interactions. Synaptotagmin III is involved in calcium-dependent exocytosis of secretory vesicles in endocrine cells and neurons. Synaptotagmin IV is expressed in neuronal tissues, and has the highest mRNA levels in the hippocampus. The proximity of the Synaptotagmin IV gene to markers of several psychiatric disorders suggest an involvement of synaptotagmin IV in human disease. Synaptotagmin V is a dense-core vesicle-specific protein that regulates a specific type of calcium-regulated secretion. Synaptotagmin VI interacts with adaptor protein-2 in a calcium-independent manner. Synaptotagmin VII is widely expressed in non-neuronal tissues.
Description
This is a SYT4 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
HsT1192, KIAA1342, Synaptotagmin IV, Synaptotagmin4, SynaptotagminIV, SYT 4, Syt IV, SYT4, SytIV
Swiss Prot
Q9H2B2
Accession Number
BC036538
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of human SYT4
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.2 mg/mL
Dilution
WB 1:500-1:2000, IHC 1:25-1:100
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
48 kDa
Host or Source
Rabbit
Isotype
IgG