SOCS2 Polyclonal Antibody

• Background:

  This gene encodes a member of the suppressor of cytokine signaling (SOCS) family. SOCS family members are cytokine-inducible negative regulators of cytokine receptor signaling via the Janus kinase/signal transducer and activation of transcription pathway (the JAK/STAT pathway). SOCS family proteins interact with major molecules of signaling complexes to block further signal transduction, in part, by proteasomal depletion of receptors or signal-transducing proteins via ubiquitination. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10, interferon (IFN)-gamma and by cytokine receptors such as growth horomone receptor.

• Synonyms:

  CIS 2,CIS-2,CIS2,Cish 2,Cish2,Cytokine inducible SH2 protein 2,Cytokine-inducible SH2 protein 2,SOCS 2,SOCS-2,Socs2,SOCS2,SSI 2,SSI-2,SSI2,STAT induced STAT inhibitor 2,STAT-induced STAT inhibitor 2,STATI 2,STATI2,Suppressor of cytokine signaling 2

• CAS Number:

  9007-83-4

• Swiss Prot:

  O14508

• Accession Number:

  BC010399

• Host:

  Rabbit

• Reactivity:

  Human,Mouse,Rat

• Immunogen:

  Recombinant protein of human SOCS2

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Conjugation:

  Unconjugated

• Applications:

  IHC,ELISA

• Purification:

  Affinity purification

• Concentration:

  0.4 mg/mL

• Dilution:

  IHC 1:25-1:100

• Buffer:

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.