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GREM1 Polyclonal Antibody

CAT: 0866-RD77436A-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0866-RD77436A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to relay the sonic hedgehog (SHH) signal from the polarizing region to the apical ectodermal ridge during limb bud outgrowth. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Description
This is a GREM1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
BMP antagonist 1, Cell proliferation inducing gene 2 protein, Cell proliferation-inducing gene 2 protein, CKTSF1B1, colorectal adenoma and carcinoma 1, Cysteine knot superfamily 1, Cysteine knot superfamily 1, BMP antagonist 1, Cysteine knot superfamily BMP antag
Swiss Prot
O60565
Accession Number
BC069525
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of human GREM1
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.3 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
21 kDa
Host or Source
Rabbit
Isotype
IgG

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