DUSP22 Polyclonal Antibody

• Background:

  Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. DUSP22 dephosphorylates ERK2 MAP kinase and JNK. DUSP22 displays highest in thymus, but it is also detectable in monocytes and lymphocytes.

• Description:

  This is a DUSP22 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  Dual specificity protein phosphatase 22, DUS22, Dusp22, JNK stimulatory phosphatase 1, JNK-stimulatory phosphatase-1, JSP 1, JSP-1, JSP1, LMW DSP2, LMW-DSP2, Low molecular weight dual specificity phosphatase 2, MAP kinase phosphatase x, Mitogen activated protein kina

• Swiss Prot:

  Q9NRW4

• Accession Number:

  BC016844

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant protein of human DUSP22

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  IHC, ELISA

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  0.4 mg/mL

• Dilution:

  IHC 1:50-1:200

• Buffer:

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source:

  Rabbit

• Isotype:

  IgG