Products for Research Use Only

Cathepsin B Polyclonal Antibody

CAT: 0866-RD77348A-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0866-RD77348A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP) . Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of the encoded protein, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene.
Description
This is a Cathepsin B Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
Amyloid precursor protein secretase, APP secretase, APPS, CATB, Cathepsin B heavy chain, Cathepsin B1, CathepsinB, CPSB, CTSB, cysteine protease, OTTHUMP00000116009, OTTHUMP00000229510, OTTHUMP00000229511, OTTHUMP00000229512, OTTHUMP00000229514, OTTHUMP00000229515, OTTHU
Swiss Prot
P07858
Accession Number
BC010240
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of human CTSB
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.3 mg/mL
Dilution
IHC 1:50-1:100
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG