SLIT2 Polyclonal Antibody

• Background:

  Secreted leucine-rich repeat-containing proteins 1-3 (Slit1-3) are secreted glycoproteins that influence axonal guidance and mediate normal neural development by acting as high-affinity signaling ligands for the repulsive guidance receptor, Roundabout (Robo. Within the developing central nervous system (CNS) of different vertebrate systems, Slit proteins are expressed in equivalent regions, suggesting a conserved function among vertebrate homologs. Slit is expressed in the midline of the central nervous system in both vertebrates and invertebrates, where it functions as a regulatory factor of mesodermal cell movement during gastrulation. Slit2 is a short range inhibitory guidance cue for retinal ganglion cell (RGC) axons that may mediate spatial progression of RGCs.

• Description:

  This is a SLIT2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  Drad 1, E030015M03Rik, E130320P19Rik, FLJ14420, OTTHUMP00000158695, OTTHUMP00000217852, OTTHUMP00000217853, OTTHUMP00000217854, Slil 3, Slil3, Slit 2, Slit homolog 2 (Drosophila), Slit homolog 2, Slit homolog 2 protein, Slit homolog 2 protein C-product, Slit-2, Slit2, SLI

• Swiss Prot:

  O94813

• Accession Number:

  NP_004778

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Synthetic peptide of human SLIT2

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IHC, ELISA

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  0.3 mg/mL

• Dilution:

  WB 1:500-1:2000, IHC 1:25-1:100

• Buffer:

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  170 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG