Products for Research Use Only

CAB39 Polyclonal Antibody

CAT: 0866-RD76966A-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0866-RD76966A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Peutz-Jeghers Syndrome (PJS) is a rare hereditary disease characterized by melanocytic macules of the lips, gastrointestinal hamartomatous polyps and an increased risk for many classes of cancer. The serine/threonine kinase LKB1 (also designated STK11) has been identified as the gene mutated in PJS. LKB1 activity increases upon the binding of a regulatory complex consisting of the STE20-related adaptor-alpha (STRAD alpha) pseudo kinase and the calcium binding protein 39 (MO25 alpha) . STRAD and MO25 determine the subcellular localization of LKB1 by initiating its translocation from the nucleus to the cytoplasm, thus regulating the tumor suppressor activity of LKB1. The LKB1/STRAD/MO25 complex acts as an AMP-activated protein kinase kinase (AMPKK) .
Description
This is a CAB39 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
Cab39, CAB39, Calcium binding protein 39, Calcium-binding protein 39, CGI 66, CGI-66, CGI66, MO25 alpha, MO25, Mouse protein 25 alpha, Protein Mo25
Swiss Prot
Q9Y376
Accession Number
NP_057373
Reactivity
Human, Mouse
Immunogen
Synthetic peptide of human CAB39
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1.7 mg/mL
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
40 kDa
Host or Source
Rabbit
Isotype
IgG