ITPR2 Polyclonal Antibody

• Background :

  Inositol 1,4,5-triphosphate (IP3) functions as a second messenger for a myriad of extracellular stimuli including hormones, growth factors and neurotransmitters. Receptor tyrosine kinases indirectly increase the intracellular levels of IP3 through the activation of phospholipases such as phospholipase C (PLC), which convert phosphatidylinositol-4,5 bisphosphate into IP3 and diacylglycerol (DAG) . The inositol 1,4,5-triphosphate receptor, IP3R, acts as an inositol triphosphate (IP3) -gated calcium release channel in a variety of cell types. Three IP3 receptor subtypes have been described and are designated IP3R-I, IP3R-II and IP3R-III. IP3R-I is the predominant IP3R subtype expressed in neuronal tissues and the central nervous system, but is also expressed at high levels in the liver.

• Description :

  This is a ITPR2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  4,5-trisphosphate receptor, Inositol 1 4 5 trisphosphate receptor type 2, Inositol 1,4,5-trisphosphate receptor type 2, Inositol 145 trisphosphate receptor type 2, InsP3 R2, InsP3R2, IP3 R2, IP3 receptor, IP3 receptor isoform 2, IP3R 2, IP3R2, ITPR 2, Itpr2, ITPR2, Typ

• Swiss Prot :

  Q14571

• Accession Number :

  NP_002214

• Reactivity :

  Human

• Immunogen :

  Synthetic peptide of human ITPR2

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  IHC, ELISA

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  0.9 mg/mL

• Dilution :

  IHC 1:50-1:200

• Buffer :

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source :

  Rabbit

• Isotype :

  IgG