IPO7 Polyclonal Antibody

CAT: 0866-RD76903A-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:0866-RD76903A-01Size:20 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. Similar to importin-beta, this protein prevents the activation of Ran's GTPase by RanGAP1 and inhibits nucleotide exchange on RanGTP, and also binds directly to nuclear pore complexes where it competes for binding sites with importin-beta and transportin. This protein has a Ran-dependent transport cycle and it can cross the nuclear envelope rapidly and in both directions. At least four importin beta-like transport receptors, namely importin beta itself, transportin, RanBP5 and RanBP7, directly bind and import ribosomal proteins.
Description
This is a IPO7 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
FLJ14581, Imp 7, Imp7, Importin-7, Importin7, IPO 7, IPO7, IPO7, MGC138673, Ran binding protein 7, Ran-binding protein 7, RANBP 7, RanBP7
Swiss Prot
O95373
Accession Number
NP_006382
Reactivity
Human, Mouse
Immunogen
Synthetic peptide of human IPO7
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.5 mg/mL
Dilution
WB 1:500-1:2000, IHC 1:100-1:300
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
120 kDa
Host or Source
Rabbit
Isotype
IgG

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