DNM2 Polyclonal Antibody

• Background:

  Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described.

• Description:

  This is a DNM2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  CMT2M, CMTDI1, CMTDIB, DI CMTB, Dnm2, DYN II, DYN2, DYN2, Dynamin II, Dynamin-2, Dynamin2, DynaminII, DYNII

• Swiss Prot:

  P50570

• Accession Number:

  NP_001005360

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Synthetic peptide of human DNM2

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IHC, ELISA

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000, IHC 1:50-1:200

• Buffer:

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  98 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG