DAAM1 Polyclonal Antibody

• Background :

  Cell motility, adhesion, cytokinesis, and other functions of the cell cortex are mediated by reorganization of the actin cytoskeleton and several formin homology (FH) proteins have been associated with these processes. The protein encoded by this gene contains two FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. A key regulator of cytoskeletal architecture, the small GTPase Rho, is activated during development by Wnt/Fz signaling to control cell polarity and movement. The protein encoded by this gene is thought to function as a scaffolding protein for the Wnt-induced assembly of a disheveled (Dvl) -Rho complex.

• Description :

  This is a DAAM1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  DAAM 1, Dishevelled associated activator of morphogenesis 1, FLJ41657, KIAA0666

• Swiss Prot :

  Q9Y4D1

• Accession Number :

  NP_001257449

• Reactivity :

  Human, Mouse

• Immunogen :

  Synthetic peptide of human DAAM1

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB, IHC, ELISA

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  1.2 mg/mL

• Dilution :

  WB 1:200-1:1000, IHC 1:50-1:200

• Buffer :

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  123 kDa

• Host or Source :

  Rabbit

• Isotype :

  IgG