MANF Polyclonal Antibody

• Background:

  The protein encoded by this gene is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and promotes cell proliferation. The protein was initially thought to be longer at the N-terminus and to contain an arginine-rich region but transcribed evidence indicates a smaller open reading frame that does not encode the arginine tract. The presence of polymorphisms in the arginine-rich region, including a specific mutation that changes the previously numbered codon 50 from ATG to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus not tumor-related.

• Description:

  This is a MANF Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  Arginine rich mutated in early stage tumors, Arginine rich protein, Arginine-rich protein, ARMET, ARMET protein, ARP, Manf, MANF, Mesencephalic astrocyte derived neurotrophic factor, Mesencephalic astrocyte-derived neurotrophic factor, MGC142148, MGC142150, Protein A

• Swiss Prot:

  P55145

• Accession Number:

  NP_006001

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Synthetic peptide of human MANF

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  IHC, ELISA

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  0.1 mg/mL

• Dilution:

  IHC 1:100-1:300

• Buffer:

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source:

  Rabbit

• Isotype:

  IgG