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FZD6 Polyclonal Antibody

CAT: 0866-RD76603A-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0866-RD76603A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants, some of which do not encode a protein with a predicted signal peptide.
Description
This is a FZD6 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
Frizzled 6 seven transmembrane spanning receptor, Frizzled drosophila homolog of 6, Frizzled family receptor 6, Frizzled homolog 6 (Drosophila), Frizzled homolog 6, Frizzled-6, Frizzled6, Fz 6, Fz-6, Fz6, FZD 6, Fzd6, FZD6, Hfz 6, hFz6, NDNC10
Swiss Prot
O60353
Accession Number
NP_001158087
Reactivity
Human, Mouse
Immunogen
Synthetic peptide of human FZD6
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.2 mg/mL
Dilution
IHC 1:100-1:300
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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