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SCN1A Polyclonal Antibody

CAT: 0866-RD76553A-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0866-RD76553A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Voltage-gated sodium channels are membrane protein complexes that play a fundamental role in the rising phase of the action potential in most excitable cells. Alpha subunits, such as SCN11A, mediate voltage-dependent gating and conductance, while auxiliary beta subunits regulate the kinetic properties of the channel and facilitate membrane localization of the complex. Aberrant expression patterns or mutations of alpha subunits underlie a number of disorders. Each alpha subunit consists of 4 domains connected by 3 intracellular loops; each domain consists of 6 transmembrane segments and intra- and extracellular linkers.
Description
This is a SCN1A Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
Brain sodium channel type I, EIEE6, FEB3, FEB3A, FHM3, GEFS+2, GEFSP2, HBSC I, HBSCI, NAC1, Nav 1.1, RBI, SCN1, Scn1a, SCN1A, SMEI, Sodium channel protein brain I alpha subunit, Sodium channel protein brain I subunit alpha, Sodium channel protein type 1 subunit alpha, Sodiu
Swiss Prot
P35498
Accession Number
NP_001159435
Reactivity
Human, Rat
Immunogen
Synthetic peptide of human SCN1A/2A/3A/4A/5A/8A/9A/10A/11A/12A
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.3 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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