DDR2 Polyclonal Antibody

• Background:

  Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation, and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane, and cytoplasmic regions. This gene encodes a member of a novel subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain.

• Description:

  This is a DDR2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  CD167 antigen-like family member B, CD167b, CD167b antigen, Cell migration inducing protein 20, DDR 2, DDR2, DDR2, Discoidin domain containing receptor 2, Discoidin domain receptor 2, Discoidin domain receptor family member 2, discoidin domain receptor tyrosine ki

• Swiss Prot:

  Q16832

• Accession Number:

  NP_006173

• Reactivity:

  Human, Mouse

• Immunogen:

  Synthetic peptide of human DDR2

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  IHC, ELISA

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  0.3 mg/mL

• Dilution:

  IHC 1:50-1:200

• Buffer:

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source:

  Rabbit

• Isotype:

  IgG