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AGXT Polyclonal Antibody

CAT: 0866-RD76452A-01Size: 20 µLDry Ice: NoHazardous: No
CAT#: RD76452A-01Size: 20 µL
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PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Serine—pyruvate aminotransferase is an enzyme that in humans is encoded by the AGXT gene. This gene is expressed only in the liver and the encoded protein is localized mostly in the peroxisomes, where it is involved in glyoxylate detoxification. Mutations in this gene, some of which alter subcellular targetting, have been associated with type I primary hyperoxaluria. Defects in AGXT are the cause of hyperoxaluria primary type 1 (HP1), also known as primary hyperoxaluria type I (PH1) and oxalosis I. HP1 is a rare autosomal recessive inborn error of glyoxylate metabolism characterized by increased excretion of oxalate and glycolate, and the progressive accumulation of insoluble calcium oxalate in the kidney and urinary tract.
Description
This is a AGXT Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
AGT, AGT1, Agxt, AGXT1, Alanine glyoxylate aminotransferase, Alanine glyoxylate aminotransferase3, Alanine--glyoxylate aminotransferase, EC 2.6.1.44, EC 2.6.1.51, Hepatic peroxisomal alanine glyoxylate aminotransferase, Hepatic peroxisomal alanine:glyoxylate aminot
Swiss Prot
P21549
Accession Number
NP_000021
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide of human AGXT
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.6 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
43 kDa
Host or Source
Rabbit
Isotype
IgG

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