MAP2K2 Polyclonal Antibody

CAT: 0866-RD76344A-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:0866-RD76344A-01Size:20 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene.
Description
This is a MAP2K2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
Cardiofaciocutaneous syndrome, CFC syndrome, CFC4, Dual specificity mitogen activated protein kinase kinase 2, Dual specificity mitogen-activated protein kinase kinase 2, ERK activator kinase 2, FLJ26075, MAP kinase kinase 2, map2k2, MAPK / ERK kinase 2, MAPK/ERK k
Swiss Prot
P36507
Accession Number
NP_109587
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide of human MAP2K2
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:1000-1:5000, IHC 1:100-1:300
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
44 kDa
Host or Source
Rabbit
Isotype
IgG

Related Products

CatalogName
RD268110A-01Phospho-MAP2K1（S217）/MAP2K2（S221） Polyclonal Antibody
RD85592A-01MAP2K2 Monoclonal Antibody
RD85591A-01MAP2K2 Monoclonal Antibody
RD267097A-01MAPK1/MAPK3 Polyclonal Antibody
RD266921A-01MAPK1/MAPK3 Polyclonal Antibody
RD268077A-01Phospho-MAP2K6(S207)/MAP2K3(S189) Polyclonal Antibody
RD88846A-01MAP4K2 Polyclonal Antibody
RD82700A-01MAP2K6 Polyclonal Antibody
RD75302A-01MAP2K5 Polyclonal Antibody
RD70371A-01MAP2K1 Polyclonal Antibody

Alternative Products

CatalogName
MBS9134762-01MAP2K2 Polyclonal Antibody
PHE17801Anti-MAP2K2 Polyclonal Antibody
MBS9440297-01MAP2K2 Polyclonal Conjugated Antibody
E53P08002MAP2K2 Rabbit Polyclonal Antibody
TA325009MEK2 (MAP2K2) Rabbit Polyclonal Antibody
MBS8586652-01MAP2K2 Antibody

Popular Products