LRPAP1 Polyclonal Antibody

• Background:

  Low density lipoprotein receptor-related protein associated protein 1also known asLRPAP1orRAPis a chaperoneproteinwhich in humans is encoded by the LRPAP1gene. LRPAP1 is involved with trafficking of certain members of the LDL receptor family including LRP1 and LRP2. It is a glycoprotein that binds to the alpha-2-macroglobulin receptor, as well as to other members of the low density lipoprotein receptor family. It acts to inhibit the binding of all know ligands for these receptors, and may prevent receptor aggregation and degradation in the endoplasmic reticulum, thereby acting as a molecular chaperone. It may be under the regulatory control of calmodulin, since it is able to bind calmodulin and be phosphorylated by calmodulin-dependent kinase II.

• Description:

  This is a LRPAP1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  39 kDa receptor-associated protein, A2MRAP, A2RAP, Alpha 2 macroglobulin receptor associated protein, Alpha 2 MRAP, Alpha-2-macroglobulin receptor-associated protein, Alpha-2-MRAP, AMRP, HBP44, Lipoprotein receptor associated protein, Low density lipoprotein recept

• Swiss Prot:

  P30533

• Accession Number:

  NP_002328

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Synthetic peptide of human LRPAP1

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IHC, ELISA

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000, IHC 1:50-1:200

• Buffer:

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  41 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG