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LRPAP1 Polyclonal Antibody

CAT: 0866-RD76343A-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0866-RD76343A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Low density lipoprotein receptor-related protein associated protein 1also known asLRPAP1orRAPis a chaperoneproteinwhich in humans is encoded by the LRPAP1gene. LRPAP1 is involved with trafficking of certain members of the LDL receptor family including LRP1 and LRP2. It is a glycoprotein that binds to the alpha-2-macroglobulin receptor, as well as to other members of the low density lipoprotein receptor family. It acts to inhibit the binding of all know ligands for these receptors, and may prevent receptor aggregation and degradation in the endoplasmic reticulum, thereby acting as a molecular chaperone. It may be under the regulatory control of calmodulin, since it is able to bind calmodulin and be phosphorylated by calmodulin-dependent kinase II.
Description
This is a LRPAP1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
39 kDa receptor-associated protein, A2MRAP, A2RAP, Alpha 2 macroglobulin receptor associated protein, Alpha 2 MRAP, Alpha-2-macroglobulin receptor-associated protein, Alpha-2-MRAP, AMRP, HBP44, Lipoprotein receptor associated protein, Low density lipoprotein recept
Swiss Prot
P30533
Accession Number
NP_002328
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide of human LRPAP1
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
41 kDa
Host or Source
Rabbit
Isotype
IgG

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