TERT Polyclonal Antibody

CAT: 0866-RD76318A-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:0866-RD76318A-01Size:20 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks. Alternatively spliced variants encoding different isoforms of telomerase reverse transcriptase have been identified; the full-length sequence of some variants has not been determined. Alternative splicing at this locus is thought to be one mechanism of regulation of telomerase activity.
Description
This is a TERT Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
CMM9, DKCA2, DKCB4, EST2, HEST2, htert, hTRT, PFBMFT1, TCS1, Telomerase associated protein 2, Telomerase catalytic subunit, Telomerase reverse transcriptase, Telomerase-associated protein 2, Telomere Reverse Transcriptase, TERT, TERT, TP2, TRT
Swiss Prot
O14746
Accession Number
NP_937983
Reactivity
Human
Immunogen
Synthetic peptide of human TERT
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1.1 mg/mL
Dilution
WB 1:200-1:1000, IHC 1:25-1:100
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
127 kDa
Host or Source
Rabbit
Isotype
IgG

Related Products

CatalogName
RDSA66537TERT Rabbit mAb
RDR-TERT-Ra-48TestsRat Telomerase Reverse Transcriptase (TERT) ELISA Kit
RD-TERT-Hu-01Human Telomerase Reverse Transcriptase (TERT) ELISA Kit
RD-TERT-Ra-01Rat Telomerase Reverse Transcriptase (TERT) ELISA Kit
RDR-TERT-Hu-01Human Telomerase Reverse Transcriptase (TERT) ELISA Kit
RDR-TERT-Ra-01Rat Telomerase Reverse Transcriptase (TERT) ELISA Kit
RD-TERT-Hu-48TestsHuman Telomerase Reverse Transcriptase (TERT) ELISA Kit
RDR-TERT-Hu-48TestsHuman Telomerase Reverse Transcriptase (TERT) ELISA Kit
RD-TERT-Hu-96TestsHuman Telomerase Reverse Transcriptase (TERT) ELISA Kit
RDR-TERT-Ra-96TestsRat Telomerase Reverse Transcriptase (TERT) ELISA Kit

Alternative Products

CatalogName
MBS8571281-01TERT Polyclonal Antibody
BS7260TERT polyclonal antibody

Popular Products