GSK3 alpha Polyclonal Antibody

• Background:

  This gene encodes a multifunctional Ser/Thr protein kinase that is implicated in the control of several regulatory proteins including glycogen synthase, and transcription factors, such as JUN. It also plays a role in the WNT and PI3K signaling pathways, as well as regulates the production of beta-amyloid peptides associated with Alzheimer's disease. May also mediate the development of insulin resistance by regulating activation of transcription factors. In Wnt signaling, regulates the level and transcriptional activity of nuclear CTNNB1/beta-catenin. Facilitates amyloid precursor protein (APP) processing and the generation of APP-derived amyloid plaques found in Alzheimer disease. May be involved in the regulation of replication in pancreatic beta-cells. Is necessary for the establishment of neuronal polarity and axon outgrowth.

• Description:

  This is a GSK3 alpha Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  DKFZp686D0638, Glycogen synthase kinase 3 alpha, Glycogen synthase kinase-3 alpha, GSK 3 alpha, GSK 3A, GSK-3 alpha, Gsk3a, GSK3A, GSK3alpha, Serine/threonine protein kinase GSK3A

• Swiss Prot:

  P49840

• Accession Number:

  NP_063937

• Reactivity:

  Human

• Immunogen:

  Synthetic peptide of human GSK3A

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  IHC, ELISA

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  0.4 mg/mL

• Dilution:

  IHC 1:50-1:200

• Buffer:

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source:

  Rabbit

• Isotype:

  IgG