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GRPR Polyclonal Antibody

CAT: 0866-RD76278A-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0866-RD76278A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene.
Description
This is a GRPR Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
BB2, Bombesin BB2 receptor, bombesin receptor 2, Gastrin Releasing Peptide Receptor, Gastrin-releasing peptide receptor, GRP preferring bombesin receptor, GRP R, GRP-preferring bombesin receptor, GRP-R, Grp/bombesin receptor, Grpr, GRPR
Swiss Prot
P30550
Accession Number
NP_005305
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide of human GRPR
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1.1 mg/mL
Dilution
WB 1:200-1:1000, IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
43 kDa
Host or Source
Rabbit
Isotype
IgG

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