Fibulin 5 Polyclonal Antibody

• Background:

  The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3) .

• Description:

  This is a Fibulin 5 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  ADCL2, ARCL1A, ARMD3, Dance, Developmental arteries and neural crest EGF like protein, Developmental arteries and neural crest EGF-like protein, EVEC, Fbln5, FBLN5, FIBL 5, FIBL-5, Fibulin-5, FLJ90059, UP50, Urine p50 protein

• Swiss Prot:

  Q9UBX5

• Accession Number:

  NP_006320

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Synthetic peptide of human FBLN5

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  IHC, ELISA

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1.2 mg/mL

• Dilution:

  IHC 1:50-1:200

• Buffer:

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source:

  Rabbit

• Isotype:

  IgG