IKBIP Polyclonal Antibody

• Background:

  IKIP (Inhibitor of nuclear factor kappa-B kinase-interacting protein, IKK-interacting protein) is a single-pass membrane protein that shares a common promoter with APAF1. APAF1 and IKIP are both induced by X irradiation, however, the two gene products are transcribed in different directions. The IKIP gene is believed to be a target for p53 as expression of IKIP has been shown to promote apoptosis. IKIP has four known isoforms, three of which are found traversing the endoplasmic reticulum membrane. IKIP isoform 4 has a deletion of the transmembrane region which leads to a homogenous distribution of the protein within the cell. The IKIP gene products are expressed in vascular endothelial cells, while the isoform 4 has also been detected in lung, kidney, spleen, thymus and skeletal muscle.

• Description:

  This is a IKBIP Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  FLJ31051, I kappa B kinase interacting protein, IKBIP, IKBKB interacting protein, IKIP1, IKIP2, IKIP3, IKK interacting protein, Inhibitor of nuclear factor kappa B kinase interacting protein

• Swiss Prot:

  Q70UQ0

• Accession Number:

  BC058933

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant protein of human IKBIP

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  IHC, ELISA

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  0.4 mg/mL

• Dilution:

  IHC 1:50-1:200

• Buffer:

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source:

  Rabbit

• Isotype:

  IgG