DMRT3 Polyclonal Antibody

• Background:

  The DMRT (doublesex and mab-3 related transcription factor) genes encode a large family of transcription factors that are related to the Drosophila doublesex proteins. Expressed primarily in the gonads, DMRT proteins contain cysteine-rich DNA-binding motifs and are thought to play an important role in sexual development. DMRT3 (doublesex and mab-3 related transcription factor 3), also known as DMRTA3, is a 472 amino acid protein that contains one DM DNA-binding domain and belongs to the DMRT family. Localized to the nucleus, DMRT3 is expressed specifically in testis and is thought to regulate transcriptional events during early sexual development. The gene encoding DMRT3 maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster.

• Description:

  This is a DMRT3 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  DMRT 3, DMRT like family A3, dmrt3, DMRT3, DMRTA3, Doublesex and mab 3 related transcription factor 3, Doublesex- and mab-3-related transcription factor 3, MGC142144, Testis specific protein

• Swiss Prot:

  Q9NQL9

• Accession Number:

  BC113584

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant protein of human DMRT3

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, ELISA

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  0.4 mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  51 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG