SPHK2 Polyclonal Antibody

• Background:

  This gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

• Description:

  This is a SPHK2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  SK 2, Sphingosine kinase 2, Sphingosine kinase type 2, SPHK2, SPHK2, SPK 2

• Swiss Prot:

  Q9NRA0

• Accession Number:

  BC006161

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant protein of human SPHK2

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IHC, ELISA

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  0.4 mg/mL

• Dilution:

  WB 1:200-1:1000, IHC 1:25-1:100

• Buffer:

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  69 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG