Products for Research Use Only

KLC1 Polyclonal Antibody

CAT: 0866-RD75567A-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0866-RD75567A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named "kinesin 2", this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos; however, the full-length nature and/or biological validity of most of these variants have not been determined.
Description
This is a KLC1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
Kinesin 2 60/70kDa, Kinesin light chain 1, Kinesin2, KLC 1, KLC, Klc1, KLC1, KNS 2, KNS 2A, KNS2, KNS2A, Medulloblastoma antigen MU MB 2.50, MGC15245
Swiss Prot
Q07866
Accession Number
BC008881
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of human KLC1
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.5 mg/mL
Dilution
WB 1:200-1:1000, IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
65 kDa
Host or Source
Rabbit
Isotype
IgG